Deca Durabolin ( “Deca”) is actually the trade name of nandrolone decanoate compound produced by Organon. This is a 19-nor compound, and as such shares essentially the same features of all other compounds of this type. One thing that is unique to Deca is the myth that created it during the last quarter century. People who have included Deca in their cycles using doses ranging from 200 to 2000mg per week. This drug was considered very powerful by Dan Duchaine in his Undergroud Steroids Handbook, as well as in many of his later writings. For many, this was and is the final word on Deca. Let’s dive into some of the reasons that made the Deca deserved myth it is today.
First of all, Deca (and Nandrolonas in general) doesn’t produce many estrogenic or androgenic side effects. This is because Deca has a rate of aromatization (conversion to estrogen by the aromatase enzyme) very low, approximately equal to the rate of testosterone (20%).
In addition, many articles assert that Deca stores water in connective tissue, thus alleviating joint pain. I have no idea where they came from these statements, or when they began. However, in a study of women in menopause, Deca improved collagen synthesis (1), and in another study deca increased bone mineral content (2). Both studies used very low doses that were too low to promote muscle growth. Based on these two studies, the athlete to use Deca only for these two effects (increasing bone mineral content and collagen synthesis) should use 100mg of Deca a week. This is actually a higher dose than that used in the two successfully. Even with half of that dose, an injection of 100mg every two weeks, HIV + patients experienced a significant increase in weight (5). Not recommended a low dose for an athlete, but this proves the strong anabolic properties of Deca. Deca is an excellent anabolic, causing nice (albeit slow) gains in quality muscle. One of its effects is nitrogen retention, which is a major factor in muscle growth and lean mass gains. In a study of low-dose (65 mg / week) and median doses of Deca (200 mg / week), both resulted in significant nitrogen retention (33-52 g nitrogen in 14 days, representing gains of 0.5 to 0, 9 kg of lean per week). Body weight increased 4.9 + / – 1.2 kg, including 3.1 + / – 0.5 kg of lean body mass and performance in exercises (cardiovascular fitness) also improved (7). Need you say that higher doses in this study produced more gains? The recommendation for weight gain is around 400 to 600 mg per week (on average).
Deca also has a long working life. With an application Deca, nandrolone levels will be stable in plasma for about 10 days, therefore it is recommended applications every at least 7 days to maintain these stable levels throughout the cycle. Interesting also was perceived higher levels of nandrolone in plasma applications in the gluteus, unlike what happens with applications in the deltoids. (This goes for all steroids oil-based).
In another study of HIV-infected men (6) we see that deca (200mgs at week 1, week 2 and 400mg 600mgs weeks 3-12) did not cause negative side effects in total or LDL cholesterol, triglycerides and insulin sensitivity, and there was a reduction in HDL cholesterol (8-10 points) in both groups. Moreover, in most studies with HIV + subjects, Deca also improved immune function. So what we know so far about this compound? So far, we know that Deca is a very safe drug for long term use, will help with joint problems, could improve immune function, and is highly (!) Anabolic and not very androgenic. That’s the good news … Now for the bad part.
Deca is known for producing weight gains, but have to be used for 12 weeks at least (by American standards). This should not cause any problems, since it is a very mild drug in terms of side effects. Many users also complain of water retention with this drug. The Letrozole seems to be the preferred choice to combat this problem. This water retention does Deca a better drug to bulking, but can be successfully used also for cutting. Now for the worst news: Deca is a progestin (as are all nandrolonas). This makes it stimulates progesterone receptors 20% more, as well as progesterone itself (3), and this opens the door to many unwanted side effects (retention, acne, etc.). It should be noted that most of these are rare, though. This may also be the main reason why Deca is a drug as suppressive when it comes to your natural testosterone levels. A single dose of 100mg of Deca causes a total (100%) reduction of natural testosterone levels, and it takes about a month for these levels back to normal! All because of a mere 100mg of Deca, restore testosterone levels more quickly and efficiently as possible.